Goat Secondary Antibodies
Cayman Chemical CreatIn Phosphate 10g
A phosphorylated form of creatine; reduces hydrogen peroxide- and ferrous ion-induced increases in MDA levels in rat heart microsomes at 10 mM; prevents hydrogen peroxide-induced decreases in aortic flow, minute work, and peak aortic pressure in isolated perfused rat hearts at 10 mM; brain levels decrease following mild traumatic brain injury in rats
Cayman Chemical 5-FormyluracIl 500mg
An oxidized form of thymine and a marker of DNA oxidative damage; incorporation of 5-formyluracil into DNA forms mispairings with thymine, cytosine, and guanine and induces mutations in E. coli; decreases the viability of V9-4 fibroblasts at 1 mM and increases their mutation frequency in a concentration-dependent manner
Cayman Chemical Ascorbyl TetraIsopalmItate 50g
A vitamin C derivative; protects against UVB-, hydrogen peroxide-, or tert-butyl hydroperoxide-induced decreases in cell viability in HaCaT keratinocytes at 100 µM; decreases IL-1α and PGE2 production in unstimulated and UVB-stimulated HaCaT keratinocytes at 20 µM; topical application increases viable epidermis thickness, stratum corneum water content, and skin smoothness and decreases skin roughness in hairless mice
Cayman Chemical 4-HexylresorcInol 100g
An alkylresorcinol; active against S. aureus, S. pyogenes, M. catarrhalis, H. influenzae, and F. necrophorum in an in vitro model of oral transmucosal delivery using 4-hexylresorcinol-containing lozenges; increases the activities of GPX, GR, and catalase in isolated human peripheral blood lymphocytes at 25, 50, or 100 µM; reduces tumor growth and increases survival in a PDX mouse model of oral mucosal melanoma at 2.5 mg/kg in combination with cisplatin
Cayman Chemical GlycocyamIn 250g
A metabolite of glycine and precursor in the biosynthesis of creatine; formed from glycine by GATM and methylated by GAMT to form creatine; levels are altered in individuals with CCDSs
Cayman Chemical ClIdInIumbromIde 1g
A gastrointestinal muscarinic receptor antagonist (Ki = 3 nM against [3H]quinuclidinyl benzilate binding in rat colonic enterocytes); a dose of 1 mg/kg slows intestinal transit and induces constipation in mice; induces serum hyperammonemia; decreases clonic, myoclonic, and tonic seizure thresholds in a murine pentylenetetrazole-induced epilepsy model
Cayman Chemical FluphenazInhydrochlorIde 500mg
A D1 and D2 receptor antagonist (Kis = 5 and 0.63 nM, respectively); binds to histamine H1, serotonin 5-HT2A, and 5-HT2B receptors (Kis = 45, 17, and 82 nM, respectively); acts as an inverse agonist at H1 and 5-HT2A receptors; a typical antipsychotic compound that induces extrapyramidal symptoms in monkeys
Cayman Chemical Goat ntI-MouseH L HRP 1mg
Goat anti-Mouse IgG, H+L conjugated to HRP Antibody: Goat polyclonal anti-Mouse IgG, H+L Enzyme: Horseradish Peroxidase Uses: ELISA and Western blot detection. Recommended dilution of 1:500-1:10,000. Starting dilution: 1:2,000.
Cayman Chemical EthosuxImIde 500mg
An anticonvulsant; increases glucose, fructose-1,6-bisphosphate, and pyruvate levels in rat brain at 200 mg/kg; reduces the severity of audiogenic seizures in a rat model of barbiturate withdrawal-induced convulsions at 400 mg/kg; inhibits PTZ- or brainstem stimulation-induced tonic hindlimb extension (ED50s = 35 and 70 mg/kg, respectively), as well as leptazol-induced clonic seizures (ED50 = 230 mg/kg), in rats; reduces resting tremor by 60% in a macaque model of Parkinson's disease induced by MPTP when administered at a dose of 150 mg/animal
Cayman Chemical L-CycloserIn 100mg
An inhibitor of sphingolipid synthesis and aminotransferases; inhibits bacterial SPT 100 times more potently than D-cycloserine; inhibits SPT activity up to 86% in a dose-dependent manner in mouse brain microsomes following administration of doses ranging from 25-200 mg/kg; inhibits SPT in rabbit aorta and several aminotransferases in vitro and in vivo in rat; inhibits the growth of M. tuberculosis through branched chain aminotransferase inactivation, and it does so more rapidly and potently than D-cycloserine (MICs = 0.3 and 2.3 UG/ml, respectively)
Cayman Chemical CyclosporIn H 10mg
A natural cyclic undecapeptide that selectively antagonizes the formyl peptide receptor at concentrations ranging from 0.1 to 10 µM
Cayman Chemical ngIotensIn II InhIbItr50mL
An angiotensin II (AII) inhibition cocktail has been developed by Bertin Pharma in order to fix physiological concentration of AII in biological samples
Cayman Chemical ArachIdonyl-L-carnItInchl 25mg
An acylcarnitine formed from carnitine conjugated to arachidonic acid; may be useful as a marker of mitochondrial dysfunction